4-[(2,5-Dimethyl-1,3-thiazol-4-yl)methyl]-4-hydroxy-2-methylisoquinoline-1,3(2H,4H)-dione
2010
In the title isoquinolinedione derivative, C16H16N2O4, the piperidine ring in the tetrahydroisoquinoline unit adopts a half-boat conformation. The essentially planar oxazole ring [maximum deviation = 0.004 (2) A] is inclined at a dihedral angle of 36.00 (8)° to the tetrahydroisoquinoline unit. In the crystal structure, pairs of intermolecular C—H⋯O and O—H⋯N interactions link the molecules into chains incorporating R22(9) ring motifs. Two neighbouring chains are further interconnected by intermolecular C—H⋯O interactions into chains two molecules wide along the a axis.
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