Amiloidose cardíaca isolada: Relato de caso

Amiloidose cardiaca e causada por um deposito amiloide entre as fibras cardiacas que pode levar a disturbio de conducao, cardiomiopatia restritiva, baixo debito e comprometimento atrial isolado. Relata-se caso de paciente feminina, 66 anos que ha tres anos iniciou com perda de peso significativa (40,4 kg)evoluindo com edema de membros inferiores. Na investigacao observou-se aumento cardiaco global, e o ecocardiograma evidenciou cardiopatia restritiva infiltrativa e derrame pericardico. Pela alta suspeicao clinica, solicitou-se ressonância magnetica cardiaca que foi altamente sugestiva de amiloidose cardiaca.O diagnostico definitivo se confirma pela biopsia endomiocardica, porem a ressonância cardiaca e descrita como bom metodo diagnostico com raros resultados falso-positivos. Cardiac amyloidosis is caused by amyloid deposits in cardiac fibers that can lead to conduction disturbance, restrictive cardiomyopathy, low output and isolated atrial involvement. This case report described a female patient, 66 years old, with significant weight loss (40.4kg) that began three year sago, progressing to lower limb edema. On investigation, overall cardiac enlargement was noted,with the echocardiogram showing infiltrative restrictive cardiomyopathy and pericardial effusion. High clinical suspicions prompted a request for a cardiac MRI that strongly suggested cardiacamyloidosis. Although definitive diagnoses require endomyocardial biopsies, cardiac MRI is described as a good diagnostic method with rare false-positive results.