FTOX037 Cisplatin-induced DNA damage and neurotoxicity: Neuroprotection by coenzyme Q10

Coenzyme Q10 (ubiquinone) is a liposoluble provitamin that is endogenously synthesized and naturally found in various foods items. It is predominantly located in the inner mitochondrial membrane, where it is involved in reactions necessary to carry out oxidative phosphorylation via the electron transport chain. Coenzyme Q10 has attracted attention for being a mitochondrial antioxidant, decreasing DNA damage and maintaining genome stability.