Interactions of microplastics, antibiotics and antibiotic resistant genes within WWTPs.

Abstract Microplastics (MPs) have been detected in atmosphere, soil, and water and have been characterized as contaminants of emerging concern. When exposed to these environments, MPs interact with the chemical compounds as well as the (micro)organisms inhabiting these ecosystems. This paper overviews the interactions and significant factors influencing the sorption process of antibiotics on MPs since distinct interactions are developed between MPs and antibiotics. The interplay between the MPs and the antibiotic resistant genes (ARGs) microbial hosts is presented and the important factors that may shape the plastisphere resistome are discussed. The interactions of MPs, antibiotics and antibiotic resistant bacteria (ARB) and ARGs in wastewater treatment plants (WWTPs) were discussed with the aim to provide a perspective for better understanding of the role of WWTPs in bringing together MPs, antibiotics and ARB/ARGs and further as release points of MPs carrying antibiotics, and ARB/ARGs.