Body adiposity predictors of vitamin D status in nondialyzed patients with chronic kidney disease: A cross-sectional analysis in a tropical climate city

Abstract Objectives The association of vitamin D status with high body adiposity is poorly investigated in the chronic kidney disease (CKD) population. The aim of the present study was to describe vitamin D status and to identify body adiposity predictors of vitamin D deficiency, in a nondialyzed CKD population inhabiting a tropical city. Methods This cross-sectional study included patients with CKD, defined as estimated glomerular filtration rate (eGFR) Results We studied 244 patients (54.9% men; n = 134) with median eGFR = 29.1 mL/min and BMI 26.1 kg/m 2 , comprising 58.2% (n = 142) with overweight/obesity. The vitamin D status was sufficient (≥30 ng/dL) in 43%, insufficient (20–30 ng/dL) in 37%, and deficient ( P  = 0.03; BAI: OR, 1.9; 95% CI, 1–3.8; P  = 0.02), whereas BMI, DXA-trunk fat, and WHtR showed no correlation. Higher serum phosphorus and hyperparathyroidism were related ( P Conclusions Just under half of the CKD population presented sufficient concentration of 25-hydroxyvitamin D. Total body adiposity, independent of age and eGFR, regardless if evaluated by DXA or BAI, was the predictor of vitamin D deficiency, which in turn was associated with higher serum phosphorus and hyperparathyroidism, but not with IR.