Modified frailty index predicts postoperative outcomes of spontaneous intracerebral hemorrhage

Abstract Objectives Frailty is an indispensable concept among elderly. The purpose of this study was to determine the association between modified frailty index (mFI) and the postoperative outcome of surgery for spontaneous intracerebral hemorrhage (sICH). Patients and methods Outcome measures included an unfavorable outcome (modified Rankin Scale score of 4–6) or mortality at 6–8 months after hemorrhage. The prognostic ability of mFI was assessed by comparing adjusted and nonadjusted effects with the Hemphill’s ICH score. The performance of the ICH score combined with mFI was assessed for discriminative ability. Results In total, 156 patients satisfied the inclusion criteria. Multivariate analyses revealed that higher mFI was significantly associated with an unfavorable outcome (p-value = 0.004) and mortality (p-value Conclusion mFI was a useful and reliable predictor of postoperative unfavorable outcome for sICH. Frailty may be an important essence to be considered before operation for sICS in the aging society.