Clinical Spectroscopy: general discussion

Duncan Graham opened a general discussion of the paper by Pavel Matousek: Regarding the temperature measurements, how did you do them? Stokes/anti-Stokes measurement? The values are not what I'd expect and seem lower. What was the wavelength and power of the laser and did you calculate what you thought the temperature measurement should be based on that? How far does the temperature gradient reach? The scattering absorption ration changes with nanoparticle size and composition. Have you thought about using more highly absorbing nanoparticles such as hollow gold nanoshells?