Oxidative stress in birds: Effects of heavy metals and pharmaceuticals

s / Toxicology Letters 221S (2013) S59–S256 S111 notmention the use of EC10 and only NOEC is stated. OECD considered the NOEC inappropriate as e.g. influenced by fortuities of test concentration selection. Itwas recommended that theOECDshould move towards a regression-based estimation procedure and phase out NOEC. The presented case shows that an environmentally favourable compound could be erroneously considered of high concern due to its desirable flat dose–response curve and use of NOEC. http://dx.doi.org/10.1016/j.toxlet.2013.05.178