Importance of acidophilic fine granulation cells in the corticotropic activity of the adenohypophysis

: The cyto-immunological tests prove that anti-ACTH (17-39) immunserums do not become localized only on beta cells of anterior lobe of Man's pituitary. They can also react upon cells with slender erythrosinophilic granules. Normally, these cells are very scattered. However, we have established that they were particulary numerous in the pituitary of six infants suddendly deceased. Conspicuously, these cells with acidophilic granulations correspond to a stage of corticotropic cells maturation.