Efectividad y seguridad del uso de micronutrientes en polvo para tratamiento de niños con anemia: revisión sistemática

Abstract Objective: To estimate the effectiveness of micronutrient powder use compared to other interventions for the treatment of children with anemia. Methodology: A systematic review was carried out in the following databases: Medline, EMBASE, CENTRAL, LILACS, Psycinfo, Clinicaltrials.gov, Google scholar, open gray and conference abstracts. There was no language restriction, only controlled clinical trials were considered, until January 2017. Results: A total of 14,735 articles were identified, of which three studies met the inclusion criteria: Kounnavong, 2011, Lemaire, 2011 and Hirve, 2007. The Kounnavong study concluded that MMP supplementation had positive effects in reducing the prevalence of anemia and in improving hemoglobin concentration; in the Hirve study there was a significant increase in hemoglobin at 3 and 8 weeks at all groups with no significant differences between them. Finally in the Lemaire study hemoglobin was higher for subjects randomized in the group receiving MNP at 2 months. Conclusions: It is not possible to estimate the effectiveness of micronutrient powder use compared to other interventions for the treatment of children with anemia, due to the insufficiency and clinical heterogeneity of the included studies.