Renal sarcoidosis presenting as renal failure: report of three cases with interstitial nephritis and normocalcemia Insuficiência renal como manifestação inaugural de sarcoidose: relato de três casos de nefrite intersticial e normocalcemia

„Sarcoidosis is a chronic inflammatory disorder of unknown cause. The histopathological feature is the presence of the non-caseating granuloma in any organ involved. The mechanisms most frequently implicated in renal dysfunction are due to disturbances in calcium metabolism; more rarely, granulomatous interstitial nephritis and glomerular disease may occur. The authors report three cases of sarcoidosis presented as interstitial nephritis with renal failure. Prednisolone treatment was performed at a dose of 1 mg/kg/day with partial and sustained recovery of renal function.