Plasmodium falciparum genetic crosses in a humanized mouse model

Ashley M. Vaughan,Richard S. Pinapati,Ian H. Cheeseman,Nelly Camargo,Matthew Fishbaugher,Lisa A. Checkley,Shalini Nair,Carolyn A Hutyra,François Nosten,Timothy J. C. Anderson,Michael T. Ferdig,Stefan H. I. Kappe

Plasmodium falciparum genetic crosses in a humanized mouse model

2015

Ashley M. Vaughan
Richard S. Pinapati
Ian H. Cheeseman
Nelly Camargo
Matthew Fishbaugher
Lisa A. Checkley
Shalini Nair
Carolyn A Hutyra
François Nosten
Timothy J. C. Anderson
Michael T. Ferdig
Stefan H. I. Kappe

A human-liver chimeric mouse supports the growth of recombinant Plasmodium falciparum progeny, enabling easy analysis of genetic crosses between parasite strains.

Keywords:

Functional genomics
Drug resistance
Humanized mouse
Genetic Crosses
Parasite hosting
Parasitology
Genetics
Plasmodium falciparum
Recombinant DNA
Biology

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