Mycobacterium tuberculosis EsxH inhibits ESCRT-dependent CD4(+) T-cell activation.

Cynthia Portal Celhay,JoAnn M. Tufariello,Smita Srivastava,Aleena Zahra,Thais Klevorn,Patricia S. Grace,Alka Mehra,Heidi S. Park,Joel D. Ernst,William R. Jacobs,Jennifer A. Philips

Mycobacterium tuberculosis EsxH inhibits ESCRT-dependent CD4(+) T-cell activation.

2017

Cynthia Portal Celhay
JoAnn M. Tufariello
Smita Srivastava
Aleena Zahra
Thais Klevorn
Patricia S. Grace
Alka Mehra
Heidi S. Park
Joel D. Ernst
William R. Jacobs
Jennifer A. Philips

Mycobacterium tuberculosis Esx-3 secretion substrate, EsxH, inhibits ESCRT function and blocks efficient antigen presentation to T cells during infection.

Keywords:

ESCRT
Mycobacterium tuberculosis
Antigen presentation
Secretion
Virology
Immunology
T cell
Biology
Antigen processing
Cell biology
Acquired immune system
Effector
Endosome

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