EPITHELIAL-MIOEPITELIAL CARCINOMA IN THE SOFT PALATE: CASE REPORT

Epithelial-myoepithelial carcinoma is a rare low-malignant neoplasm consisting of 1% of all tumors in the salivary glands. A 53-year-old black female patient complained of pain in the palate. Past medical history included an incisional biopsy whose histologic slices stained in hematoxylin and eosin (H&E) showed atypical glandular proliferation compatible with myoepithelial carcinoma, low-grade polymorphous adenocarcinoma, and adenoid cystic carcinoma. A reddish area of 1 cm was observed in the soft palate, with no symptoms. Faced with the lack of diagnostic definition, excisional biopsy was chosen where the anatomopathologic analysis corroborated previous findings, but immunohistochemistry showed positivity for Ki67, P63, cytokeratin 7, cytokeratin 8/18, and calponin, leading to the definitive diagnosis of epithelial-myoepithelial carcinoma. Because of the free margins observed in H&E, we chose to follow-up, who after oral rehabilitation continues without signs of local recurrence in a 2-year follow-up.