The PGC-1α -HO-1 axis, a powerful antioxidative pathway with potential to attenuate diabetic cardiomyopathy

Maayan Waldman,Michael Arad,Nader G. Abraham,Edith Hochhauser

The PGC-1α -HO-1 axis, a powerful antioxidative pathway with potential to attenuate diabetic cardiomyopathy

2020

Maayan Waldman
Michael Arad
Nader G. Abraham
Edith Hochhauser

Significance: From studies of diabetic animal models, the downregulation of PGC-1α -HO-1 axis appears to be a crucial event in the development of obesity and diabetic cardiomyopathy (DCM). In this ...

Keywords:

Pharmacology
Cell biology
Diabetic cardiomyopathy
Biology
Peroxisome
Downregulation and upregulation
Heme oxygenase
Peroxisome proliferator-activated receptor
Coactivator
Oxygenase
Diabetes mellitus

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