Optical coherence tomography based microsurgical operation system and navigation method

The invention discloses an optical coherence tomography based microsurgical operation system and a navigation method. The microsurgical operation system comprises an objective lens, an operation microscope unit, an optical coherence tomography unit, a processor and an output unit. The operation microscope unit is configured to perform two-dimensional imaging in an operative region via the objective lens. The optical coherence tomography unit is configured to perform two-dimensional tomography imaging in the operative region via the objective lens, and an imaging view of the optical coherence tomography unit is calibrated according to an imaging view of the operation microscope unit. The processor is configured to acquire navigation information on the basis of a two-dimensional imaging result of the operation microscope unit and a two-dimensional tomography imaging result of the optical coherence tomography unit, and the navigation information includes information of the operation region for performing operation and positions of surgical instruments used for operation on the operative region. The output unit is configured to output navigation information to guide the operation instruments to reach the operative region.