Dipeptidyl peptidase-IV inhibitory activity of millet protein peptides and the related mechanisms revealed by molecular docking

Abstract Dipeptidyl peptidase-IV (DPP-IV) inhibitory peptides released from foods are promising agents to combat type 2 diabetes. Millet protein supplementation can effectively ameliorate type 2 diabetes. Therefore, the objective of the study was to identify DPP-IV inhibitory peptides from millet protein and reveal the potential mechanisms. The results showed that millet protein hydrolysates (MPH) significantly inhibited DPP-IV activity compared with original millet protein (p