Method for producing a bioactive composite material

An object of the present invention, the various porous substrates, including porous compact comprising an organic polymer, a high bonding strength a coating layer mainly composed of calcium phosphate compounds in vivo and in vitro on the surface it is to provide a method for producing a bioactive composite material imparted with bioactivity for forming or growing with. Step Its solution is, to spread the solution into the interior of at least some of the pores of the substrate by immersing the porous substrate in a solution containing at least a (1) calcium ions and hydrogen phosphate ions, (2) solution characterized in that it comprises at least a step, to precipitate fine particle mainly comprising calcium phosphate compounds in the interior of intruded pores.