Childhood trauma: a risk for major depression in patients with psoriasis

ABSTRACTINTRODUCTION: A history of childhood trauma is an important determinant for understanding the development of psychiatric and physical disorders. The chronic inflammatory disease, psoriasis, has been reported to be affected by childhood psychological stressors. Early life stress is also a well-known contributor to major depression. The current study aims to clarify a possible association between levels and types of childhood trauma with psoriasis severity and major depression.METHOD: Sixty-four patients diagnosed with mild-to-severe psoriasis (male = 27, mean age = 52.51 ± 14.72 years and female = 37, mean age = 42.76 ± 14.45 years, age range = 21–77) were admitted to our study between April 2014 and September 2014. For the diagnosis of psoriasis, the single most recently developed lesion was examined dermoscopically and histopathologically. We evaluated the history of childhood trauma with the Childhood Trauma Questionnaire and diagnosis of major depression with the Mini International Neuropsychia...