Fusion protein of thymulin alpha1

The invention discloses fusion protein of thymulin alpha1. The fusion protein is formed by connecting the thymulin alpha1 or active fragments of the thymulin alpha1with a constant region of immune globulin through connecting peptide or directly. The fusion protein can be expressed in eukaryotic cells and can also be expressed in prokaryotic cells. According to the fusion protein of the thymulin alpha1, a pronucleus carrier containing a target gene is prepared through the recombination DAN technology and expressed, separated and purified in escherichia coli, and compared with archetype thymulin alpha1, the obtained fusion protein of the thymulin alpha1 is longer in in-vivo half-life period and more efficient in anti-tumor effect.