N2-(2-methoxyphenyl)pyrimidine derivatives, preparation method thereof, and pharmaceutical composition for use in preventing or treating cancer containing the same as an active ingredient

2016 
The invention N2- (2- methoxyphenyl) pyrimidine derivatives, to their preparation, and it relates to the prevention or treatment of a pharmaceutical composition for cancer containing as an active ingredient, N2- (2- accordance with the present invention methoxy phenyl) pyrimidine derivatives, their optical isomers, or pharmaceutically acceptable salts are the salts formed by excellent activity to inhibit anaplastic lymphoma kinase (ALK), this anaplastic lymphoma kinase, such as EML4-ALK, NPM-ALK in accordance with its ( ALK) has excellent therapeutic effect on cancer cells with a fusion protein, so may be useful in pharmaceutical compositions for the prevention and treatment of cancer.
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