Screening ToxCast™ for Chemicals That Affect Cholesterol Biosynthesis: Studies in Cell Culture and Human Induced Pluripotent Stem Cell–Derived Neuroprogenitors

Phillip A. Wages,Piyush Joshi,Keri A. Tallman,Hye-Young H. Kim,Aaron B. Bowman,Ned A. Porter

Screening ToxCast™ for Chemicals That Affect Cholesterol Biosynthesis: Studies in Cell Culture and Human Induced Pluripotent Stem Cell–Derived Neuroprogenitors

2020

Phillip A. Wages
Piyush Joshi
Keri A. Tallman
Hye-Young H. Kim
Aaron B. Bowman
Ned A. Porter

Background: Changes in cholesterol metabolism are common hallmarks of neurodevelopmental pathologies. A diverse array of genetic disorders of cholesterol metabolism support this claim as do multipl...

Keywords:

cholesterol metabolism
Cell biology
Toxicology
Biology
Induced pluripotent stem cell
Cell culture
Cholesterol biosynthesis
Environmental health

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations