Synthesis and enhanced electrochemical property of Au-doped cerium phosphate nanowires

Abstract Au-doped cerium phosphate (Au/CePO 4 ) nanowires (NWs) were prepared through combining hydrothermal and solvothermal methods, in which Au NP sizes and numbers could be tailored through varying chloroauric acid concentrations. The Au/CePO 4 NWs were utilized to explore a novel biosensor through coupling hemoglobin (Hb) with chitosan (Chi). Compared with Hb–Chi–CePO 4 /GC electrode, Hb–Chi–Au/CePO 4 /GC electrode exhibited a pair of much stronger redox peaks at −0.32 V. Moreover, the electrochemical properties of the Au/CePO 4 -based biosensors closely depended on their Au NP sizes and numbers. The Au(2)/CePO 4 -constructed biosensor had the most excellent electrochemical properties in comparison with CePO 4 - and other Au( x )/CePO 4 -constructed biosensors.