Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity
2015
Immune activation must be carefully tuned to respond to infection and restrained to prevent tissue damage. Here the authors show that autophagy has a role in the immune response to Candida albicans, activating NFκB in macrophages by sequestering the NFκB inhibitor A20.
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