Synthesis and Evaluation of Cardiotonic Activity of Diterpenic Butenolides.

A. San Feliciano,Manuel Medarde,Esther Caballero,B. Hebrero,Fernando Tomé,P. Prieto,M.J. Montero

Synthesis and Evaluation of Cardiotonic Activity of Diterpenic Butenolides.

1992

A. San Feliciano
Manuel Medarde
Esther Caballero
B. Hebrero
Fernando Tomé
P. Prieto
M.J. Montero

Abstract Four diterpenic cardenolide analogs have been prepared from sandaracopimaric acid and tested for inotropic activity. Three of them displayed an unexpected negative inotropic activity.

Keywords:

Terpene
Chemistry
Organic chemistry

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