Synthesis of 2,11-bis(methylidene)spermine, a new inhibitor of spermine oxidase
2016
Earlier unknown 1,12-diamino-2,11-bis(methylidene)-4,9-diazadodecane, which may be considered as an enzyme-activated inhibitor of spermine oxidase, was synthesized in 6 steps starting from 2-chloromethyl-3-chloropropene-1 in a high yield. Application of newly synthesized spermine analogue for the inhibition of spermine oxidase was discussed.
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
20
References
3
Citations
NaN
KQI