Epiretinal Macular Edema Associated With Thick Epiretinal Membranes

High-resolution imaging with spectral- domain optical coherence tomography has iden- tified an unusual group of epiretinal membranes (ERMs) in the presence of lamellar macular holes. These ERMs are unusually thick. The authors pres- ent the case of a patient with age-related macular degeneration who developed edema within a thick- ened ERM in both eyes after cataract surgery. The edema resolved with anti-vascular endothelial growth factor (VEGF) therapy. The authors propose that the VEGF-responsive fluid within these thick ERMs arose from fibrovascular tissue derived from the retina. Further studies with histopathology will be required to determine whether neovascular tis- sue is present in all cases of thickened ERMs with epiretinal edema.