Effect of early intervention on 5-year outcome in non-affective psychosis
2010
Background
Early specialised care may improve short-term outcome in first-episode non-affective psychosis, but it is unclear if these benefits endure.
Aims
To assess the long-term effect of early intervention in psychosis.
Method
Individuals with first-episode psychosis were randomised to specialised care or care as usual (trial number: [ISRCTN73679874][1]). Outcome after 5 years was assessed by case-note review.
Results
There were no significant differences in the admission rate (coefficient 0.096, 95% CI –0.550 to 0.742, P = 0.770) or the mean number of bed days (coefficient 6.344, 95% CI –46 to 58.7, P = 0.810).
Conclusions
These findings that specialist intervention did not markedly improved outcome at 5 years accord with those from a larger OPUS study. The sample size of this study was small and these results should be generalised with caution. More research is needed.
[1]: /external-ref?link_type=ISRCTN&access_num=ISRCTN73679874
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