Brain and skull

It is well established that the anatomical correlations between brain and skull are very poor and so variable as to made precise topometry difficult and doubtful. Thus, all exact topographical measurement of brain structures requires a careful choice of reliable anatomical reference points. Therefore, any precise topographical analysis of brain structures ought to be performed according to judicious and definite cerebral reference lines based on cutaneous, cranial as well as brain landmarks (Tamraz and Comair).