Antiangiogenic Activity of Tumor Necrosis Factor-α Production Regulators Derived from Thalidomide
1999
Recently, we developed novel tumor necrosis factor (TNF)-α production regulators with a phthalimide skeleton derived fromthalidomide. We show here that some of these compounds are more potent inhibitors than thalidomide of angiogenesis induced by basic fibroblast growth factor in a murine angiogenesis assay.
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