Valores de homocisteína plasmática en adultos mayores de 65 años en una institución de tercer nivel de la Ciudad de México

Objective: To determine the levels of homo cysteine (Hcy) in older adults and the possible association with the studied variables. Methodology: Cross-sectional, descriptive and exploratory design; both sexes,> 65 years. Sociodemographic and clinical characteristics were evaluated; 5 mL of blood were extracted; classification used for Hcy: Normal 5-14, μmol/L 15-29 slight, ≥ 30 high. Plasma quantitation by HPLC. Patients were grouped according to these determinations. Descriptive statistics, normality testing of Kolmogorov-Smirnov, χ2 categorical variables, unilateral ANOVA, multiple linear regression model: predictive variables (sociodemographic and clinical characteristics), dependent variable (Hcy levels). Significance level of p 85 years, widows 68.2% (p = 0.003). Media Hcy, women 22.3 ± 11.8, men 23.4 ± 11.9; General 22.7. Hcy concentration was different in all age groups; the most frequent level of this metabolite was 15-29 μmol/L with p = 0.001. In one-way ANOVA we found no differ* Unidad de Vigilancia Epidemiologica. ‡ Servicio de Rehabilitacion Geriatrica. § Servicio de Genetica. Instituto Nacional de Rehabilitacion. Direccion para correspondencia: Aurelio Tirzo Serrano Miranda Av. Mexico-Xochimilco Num. 289, Col. Arenal de Guadalupe, 14389, Deleg. Tlalpan, Mexico, Distrito Federal. Tel: 55-99-10-00, ext. 13135; 16001. E-mail: tserranomiranda71@gmail.com Recibido: 05 de noviembre de 2015. Aceptado: 02 de marzo de 2016. Este articulo puede ser consultado en version completa en: http://www.medigraphic.com/rid Palabras clave: Homocisteina, adultos mayores, tercer nivel de atencion, Mexico, hiperhomocisteinemia.