Rudimentary G-quadruplex–based telomere capping in Saccharomyces cerevisiae

Telomere capping is essential for genomic integrity. In yeast, a capping complex containing protein Cdc13 protects telomeres from degradation and from the DNA damage repair system. Yeast telomeric repeats can form G-quadruplexes, whose potential capping role is now revealed using Cdc13-impaired strains.