Detection of Inflammatory Arthritis by Using Hyperpolarized 13C-Pyruvate with MR Imaging and Spectroscopy

John D. MacKenzie,Yi-Fen Yen,Dirk Mayer,James Tropp,Ralph E. Hurd,Daniel M. Spielman

Detection of Inflammatory Arthritis by Using Hyperpolarized 13C-Pyruvate with MR Imaging and Spectroscopy

2011

John D. MacKenzie
Yi-Fen Yen
Dirk Mayer
James Tropp
Ralph E. Hurd
Daniel M. Spielman

The data presented herein suggest that the presence of inflammation may be detected at 13C-MR spectroscopy as the increased conversion of hyperpolarized 13C-pyruvate into 13C-lactate.

Keywords:

Nuclear magnetic resonance spectroscopy
Spectroscopy
Lactic acid
Inflammatory arthritis
Inflammation
Pathology
Gadolinium
Medicine
Hyperpolarized 13C-Pyruvate
Nuclear magnetic resonance
mr imaging
rats sprague dawley

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