Amino Acid Substitution Analyses of the DNA Contact Region, Two Amphipathic α-Helices and a Recognition-Helix-Like Helix outside the Dimeric β-Barrel of Epstein-Barr Virus Nuclear Antigen 1

Tomomichi Fujita,Masato Ikeda,Shuichi Kusano,Makoto Yamazaki,Sayuri Ito,Maya Obayashi,Kazuo Yanagi

Amino Acid Substitution Analyses of the DNA Contact Region, Two Amphipathic α-Helices and a Recognition-Helix-Like Helix outside the Dimeric β-Barrel of Epstein-Barr Virus Nuclear Antigen 1

2001

Tomomichi Fujita
Masato Ikeda
Shuichi Kusano
Makoto Yamazaki
Sayuri Ito
Maya Obayashi
Kazuo Yanagi

Objectives and Methods: Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA-1), which is essential for EBV latency, homodimerizes and binds to the EBV replication origin, oriP

Keywords:

DNA-binding domain
Epstein–Barr virus nuclear antigen 1
Molecular biology
DNA
Helix
Epstein–Barr virus
Virology
Amino acid
Point mutation
Antigen
Biology
Biochemistry
Virus
contact region
Amphiphile

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