Effect of anthocyanins on human connective tissue metabolism in the human
1996
Background Diabetic retinopathy can lead to blindness. This is due to an abnormally increased synthesis of connective tissue in order to a) repair leaking capillaries and b) formation of new capillaries. Method Twelve adult diabetics were treated with 600 mg anthocyanosides per day for two months. Samples of gingiva tissue were taken before and after treatment. Incubated with radio-active labeled aminoacids, the measure of radioactivity from different connective tissue extracts can show a changed protein biosynthesis activity. Results The use of radio-active labeled aminoacids show significant decrease of biosynthesis-activity of connective tissue especially polymeric collagene and structure-glycoproteins by anthocyanoside medication. Conclusions Anthocyanosides help to prevent diabetics from injuries caused by malfunction of synthesis-activities throughout normal diabetic medical treatment.
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