Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10
2017
The signaling receptor Notch is required for the generation of marginal zone B cells. Hammad and colleagues show that Notch signaling activates the kinase Taok3 and surface expression of the metalloproteinase ADAM10, which commits transitional B cells to the marginal zone B cell fate.
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