Advanced Practice Registered Nurses (APRN): Educating Present and Future Leaders in Palliative Care (S744)

patient-reported factors (i.e., depression, spiritual well-being, symptoms) were used to determine which factors were independently associated with each outcome. Results. The study included 384 Veterans (mean age 68 years, 97% male, 82% white) with a mean KCCQ score of 38, indicating reduced health status. Demographics and clinical covariates were not significantly associated with the outcomes. Depression, spiritual well-being and several nonHF-specific symptoms were independently associated with HF-specific QOL (p<0.0001) and health status (p<0.0001). Only depression and spiritual well-being were associated with overall QOL (p<0.0001). Variability due to patient-reported factors (i.e., depression, spiritual well-being, chest pain, numbness, dizziness) was 32% for HF-specific QOL, 29% for HF-specific health status and 23% for overall QOL. Conclusions. Depression, spiritual well-being and several non-traditional HF-related symptoms are modifiable patient-reported factors that were independently associated with HF-specific QOL and health status in symptomatic HF patients. Implications for research, policy, or practice. A comprehensive palliative care approach that targets patient-reported factors may influence HF-specific QOL and health status.