Aislamiento y caracterización de metabolitos de hojas de Croton linearis Jacq.
2015
From an ethanolic extract of Croton linearis Jacq. leaves were isolated and identified a total of 7 compounds: two long chain alcohols: 2-methyl-tretradecan-2-ol (1) y el hexacosanol (3); a linear saturated hydrocarbon: tetracosane (2); three fatty acids: stearic (4), 5,8 -dien-tetradecanoic (6) and oleic acid (7); as well as a tri -methoxylated flavone: 5-hydroxy-3,7,4′-trimethoxyflavone (5). Structures of the compounds were elucidated by spectroscopic techniques as Nuclear Magnetic Resonance 1D and 2D (1H and 13C), as well as Gas Chromatography/Mass Spectrometry and Kovats retention indexes when necessary. The substituent positions were assigned based on combination of heteronuclear HMBC and HMQC as well as homonuclear1H-1H-COSY experiments. All identified compounds constitute a first report for the specie in study. Keywords: Croton linearis, metabolites, isolation, flavone.
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