The influence of HRT on bone mineral dencity, condition of parodontal complex tissue, clinical implications of articulated syndrome in postmenopausal women

Introduction . To evaluate the effect of hormone replacement therapy on periodontal treatment outcomes complex, bone mineral density and articular syndrome in a group of postmenopausal women. Materials and methods . We carried out an exploration of 32 postmenopausal women aged 50-59 years , with chronic periodontitis, postmenopausal osteoporosis, hand osteoarthritis. The control group (n=14) didn’t receive HRT (HRT–). The test group (n=18) –received HRT (HRT+).All subjects were examined by recording the following: plaque index (PI), sulcus bleeding index (SBI), periodontal pocket depth (PD), Dreiser`s index, VAS pain score. Measurements were recorded at the baseline, 1 month, 3 months, and 6 monthsю Results. The significant decline was revealed in all of the values (PI, SBI, PD) in HRT+ compare to HRT-. After 6, 12 months, in the periodontal area had been stabilized in the HRT+ group. 11.2% reduction was indicated in the lumbar spine and 8,15% reduction in the femoral neck within the HRTafter 1 year. The significant decrease was discovered in VAS pain score, Dreiser`s index, painful joints quantity in HRT+. Conclusions : 12-week HRT was highly effective in periodontal treatment outcomes (significant decrease in PI, SBI, PD after 3 months). BMD of the femoral neck and lumbar spine is reduced within 1 year in patients with MHTcompared with MHT +.In the group of MHT +, compared with the group of MHTand baseline data, after 3 months there was a significant improvement in the number of painful joints, the level of pain, the Dreiser index, a positive effect persists until the end of the study.