Antianemic Activity of Coconut (Cocos nucifera) Haustorium Waste Filtrate in Mice Induced by Sodium Nitrite

This study aims to determine the anti-anemia activity of coconut milk (Cocos nucifera Haustorium) waste against mice induced by sodium nitrite orally for 43 days. The condition of anemia was determined by calculating the hemoglobin level using the Point of Care Test (POCT) method with the easytouch® GCHb tool and the resulting Hb level was 7.96 ± 0.05 g / dL. After the anemia condition is achieved, the test treatment is given for 21 days by dividing the mice into 5 treatment groups each consisting of 3 mice. The blank group was given distilled water, the control group was given Inbion® supplements at a dose of 0.65 mg / 20 g BW, groups I and II were given coconut concentrate filtrate at a dose of 5g / kg and 15g / kg, respectively. Then measured the hemoglobin level and the number of erythrocytes. Based on the results of the study, the average hemoglobin levels of the blank, control, I and II groups were 13.9 g / dL, 15.4 g / dL, 16.03 g / dL and 16.8 g / dL, respectively. The number of erythrocytes during anemia was 1,750,000 / mm3 and after giving coconut kentos was 8,260,000 / mm3. From this study it can be concluded that the highest anti-anemia activity possessed by coconut kentos waste filtrate is at a dose of 15g / kgBW and has a significant difference in hemoglobin levels (p <0.05) with the blank group.