Study of antioxidant and anticancer activity of natural sources
2012
The use of Synthetic antioxidants is been widely restricted because of their reported toxic and carcinogenic effects. Thus now there is considerable interest being focused towards finding antioxidants from natural sources with any unlikely effects. There is also considerable evidence which indicates lower risk of Cancer in people with high intake of fruits and vegetables, which is presumingly because of the antioxidant or other active compounds present in them. The present study was conducted to determine antioxidant activity of Streptomyces sps.PDS1,commercially available Red Wine and Saccharomyces cerevisiae MTCC-181 using the Ferric reducing assay and to study the anticancer activity of Green Tea and Citrus limetta against human lung carcinoma cell line A549 using the MTT assay.The isolates of Streptomyces sps.PDS1 was found to have more antioxidant activity Saccharomyces cerevisiae.The antioxidant potential was then correlated with the total phenol and flavonoid content.The filtrates of Green Tea showed maximum anticancer activity against cancer cell line A549 as compared to that of Citrus limetta.
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