miR-136 improves renal fibrosis in diabetic rats by targeting down-regulation of tyrosine kinase SYK and inhibition of TGF-β1/Smad3 signaling pathway.

Lei Liu,Xinlu Pang,Wenjun Shang,Guiwen Feng,Zhigang Wang,Junxiang Wang

miR-136 improves renal fibrosis in diabetic rats by targeting down-regulation of tyrosine kinase SYK and inhibition of TGF-β1/Smad3 signaling pathway.

2020

Lei Liu
Xinlu Pang
Wenjun Shang
Guiwen Feng
Zhigang Wang
Junxiang Wang

Objective: To investigate the way that miR-136 regulated spleen tyrosine kinase (SYK) and transforming growth factor-β1 (TGF-β1)/Smad3 signaling pathways on renal fibrosis.Methods: 100 male SD (Spr...

Keywords:

Downregulation and upregulation
tgf β1 smad3
Internal medicine
renal fibrosis
Endocrinology
Syk
Signal transduction
Cancer research
Medicine
Tyrosine kinase
Diabetes mellitus

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