related microRNA-21 mismatch repair methods and in colorectal cancer
2011
A composition of matter for use in the treatment of colorectal cancer (CRC) in a patient having decreased expression of hMSH2 protein (protein complex recognition mismatch repair (MMR)) and responds to treatment with 5- fluorouracil, the composition comprising: an effective amount of miR-21 antisense and a pharmaceutically acceptable formulation thereof, wherein miR-21 is SEQ ID. No.12.
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