Recommendations for fluorine-18 production

Abstract Data for the production of fluorine-18 (t 1/2 = 109.6 min; β + = 100%) are reviewed. The experience of some well-established European centres for positron emission tomography (PET), in the routine production of fluorine-18 for the purpose of labelling radiopharmaceuticals, is described. This experience is evaluated, along with published data, to give practical and technical recommendations to new PET group entering this key area.