Application of Models and Modeling in Biomedicine

Background: The roles of modelling, models, and simulations are undoubtedly essential in health care, as is medical informatics. Modelling and the simulation in clinical medicine are very important. The analysis of clinical decisions is a logical method based on the probability theory and theory of usefulness. Objective: The aim of this study was to describe application of the most important models in medical practice. Methods: Authors used descriptive method of explanation models in the praxis based on searching scientific literature deposited on online databases. Results and Discussion: Two factors that have influenced to the decision process: a) Degree of uncertainty about future events; b) Usefulness of outcomes in any particular case. The clinical decision problem analysis process demands: a) Explicit formalization of a decision making problem or the description of the medical problem decision with a registration of all possible actions which have to be undertaken and registration of all the possible so determined outcomes. B) Construction of the decision tree which presents all described actions and outcomes with predictions of the probabilities and the choice of the most optimal action based on the probability outcome and its use. Conclusion: Models must be recognised as a complex tool with many variables, and to produce a good model is to fully realise the structure and function of the real system in place, and once this is realised, only then can a health care system be totally revaluated and changed for large improvements.