Synthesis and Antioxidant Activity of Some Flavone Derivatives

Some novel flavones were synthesized by condensation reactions of substituted ketones with substituted aldehydes to form chalcones. The formed 2-hydroxyl substituted chalcone made to react with polyethylene glycol-400 (PEG-400) with catalytic amount of iodine, produces flavone derivatives. The synthesized derivatives were characterized by spectral analysis and revealed to be therapeutically active as antioxidant agents.