Treatment intensity differences in screen-detected and community-detected early stage breast cancer (ESBC).

1579 Background: The value of population based mammographic screening has been questioned by those who believe that the reduction in mortality from earlier diagnosis is outweighed by harms including overdiagnosis and overtreatment as well as harms of false positive recall for assessment. Intensity of treatment received is rarely mentioned in the debate. We hypothesised that screen-detected (SD) cancers would receive less extensive surgical treatment and less intense adjuvant therapies than community-detected (CD) cancers. If demonstrated, the extent of these differences would form an important component of the debate over the role of mammographic screening. Methods: Retrospective analysis of a consecutive cohort of female patients aged 40-75 and managed for ESBC between 2009-2013 within a large metropolitan Breast Service in Melbourne, Australia, diagnosed either via a population screening program (SD) or clinically referred to the Service (CD). Data on patient characteristics, symptoms, tumor characteris...