TRANEXAMIC ACID DECREASES BLOOD TRANSFUSIONS IN REVISION HIP SURGERY

2018 
BackgroundThe use of tranexamic acid (TEA) can significantly reduce the need for allogenic blood transfusions in elective primary joint arthroplasty. Revision total hip arthroplasty requires increased utilization of post-operative blood transfusions for acute blood loss anemia compared to elective primary hip replacement. There is limited literature to support the routine use of TEA in revision THA.MethodsWe performed a retrospective review of 161 consecutive patients who underwent revision total hip arthroplasty from 2012–14 at a single institution by two fellowship-trained surgeons. We compared the transfusion requirements and the post-operative hemoglobin drop of the TEA Group (109 patients, 114 hips) versus the No TEA group (52 patients, 56 hips). Our standard protocol for administering TEA is 1000mg IV at incision, and the same dose repeated two hours later. The No TEA group did not receive the medication because of previous hospital contraindication criteria.ResultsThe transfusion rate was significa...
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