Abstract 059: Local Endothelial and Smooth Muscle Genomic Instability Reproduce Specific Features of Cardiovascular Aging

Paula K. Bautista Niño,Eliana Portilla-Fernandez,Alexandra Santu,Catherine M. Shanahan,Anton J.M. Roks

Abstract 059: Local Endothelial and Smooth Muscle Genomic Instability Reproduce Specific Features of Cardiovascular Aging

2018

Paula K. Bautista Niño
Eliana Portilla-Fernandez
Alexandra Santu
Catherine M. Shanahan
Anton J.M. Roks

Nuclear and mitochondrial DNA damage contribute to aging and related cardiovascular disease. To explore if the aging features are cell autonomous we compared cardiovascular function of mice with a ...

Keywords:

Genome instability
Endocrinology
Medicine
Internal medicine
smooth muscle
Diabetes mellitus

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