Airway invasive aspergiliosis:one case report and review of literature

Objective To investigate the clinical manifestations,diagnosis and treatment of airway invasive aspergillosis.Methods The clinical data of one case of airway invasive aspergillosis in our hospital was reported and the related literatures were reviewed and analyzed.Results A 49-year-old female patient complained of intermittent cough,sputum and fever for one month.Chest computer tomography showed consolidation tips of left lung lower lobe.After anti-inflammatory,anti-tuberculosis treatment for one month in other hospital,the patient had no significant improvement in symptoms.In our hospital,the patient received bronchoscopic examination and the result was aspergillus infection in biopsy tips.After anti-fungal therapy and repeated tracheal endoscopic high-frequency coagulation therapy,the patient's symptoms improved.Conclusions Airway invasive aspergillosis is uncommon.Aspergillus in the airway lumen grows as lumps,it causes bronchial obstruction and expansion,accompanies rapid progression and strong invasion.Early adequate anti-fungal therapy and bronchoscopy involvement of local high-frequency coagulation therapy can lead to satisfactory results. Key words: Airway; Invasive; Aspergillosis